The correct answer focuses on the operational mechanics of desktop flows within Microsoft Power Automate. When desktop flows are initiated, they operate on your local machine and rely on the physical inputs from your keyboard and mouse to perform a sequence of actions as designed. If you use your keyboard or mouse while a desktop flow is running, it can disrupt the execution of the flow, potentially causing errors or unintended actions. Hence, it's crucial to avoid interacting with the machine during this time to ensure that the flow performs as intended, without any interference.
In contrast, manual triggers can be one way to initiate flows, but they are not the only method. For example, flows can be automated based on scheduled times or specific events, making the initiation statement too narrow. While desktop flows focus primarily on local machine interactions, cloud flows are designed to connect with online services, but desktop flows typically do not connect to services like Outlook or Teams directly in the context provided. Furthermore, flows indeed require connections to services to interact with them appropriately, so they cannot operate without a predefined connection if they are to interact with external data sources.